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Real members of MyMigraineTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Massive Migraine And My Sumatriptan Is Not Working. Can I Take Tylenol Or Ibuprofen With It? I’m Out Of All My Other Meds.

A MyMigraineTeam Member asked a question 💭
Aledo, TX
January 8
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A MyMigraineTeam Member

I am on Qulipta daily and Ubrelvy when the Qulipta doesn't get it. Still there are days I suffer so that I am still trembling and crying, the meds are of no help. It's a living hell.

January 11
A MyMigraineTeam Member

I took Emgality on 11/26/24 and it's lessened my chronic migraines and cluster headaches. Although because of the GI side effect I'm not taking it any longer and have an appointment on 11/28/25 to get botox. I take Topiramate and Gabapentin for my migraines as well. I take Rizatriptan when I get a migraine and a lot of the time it helps. If it doesn't help or I have a headache I take 1,000mg Tylenol capsules. Ibuprofen doesn't work for my migraines and headaches. I'm wishing you the best 👌 and hope you get better.

January 11
A MyMigraineTeam Member

If your sumatriptan isn't working, taking Tylenol (acetaminophen) or ibuprofen may help, as they are commonly used for migraine relief. However, avoid overusing medications, as this can lead to medication overuse headaches. It's best to consult your doctor before combining treatments, especially if you're unsure about Show Full Answer

If your sumatriptan isn't working, taking Tylenol (acetaminophen) or ibuprofen may help, as they are commonly used for migraine relief. However, avoid overusing medications, as this can lead to medication overuse headaches. It's best to consult your doctor before combining treatments, especially if you're unsure about interactions or your health history. If the migraine persists, seek medical advice promptly.

January 8
A MyMigraineTeam Member

I'm sorry you're in so much pain. I take Qulipta daily and get Botox Injectjons every 3 months. I also take Gabapentin 3 times a day. When I get them I take Rizatriptan. Times I get the migraines and nothing helps. I need to lie down in dark room, with cool cloth to my eyes and forehead. I've taken Extra Strength Tylenol for Migraines. I don't know the difference between Extra Strength Tylenol and the Exta Strength one for migraines. I hope and pray you get relief from your migraine.

January 11
A MyMigraineTeam Member

I would say ask your doctor first

January 11

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