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What Causes Migraine? The Risk Factors You Need To Know

Medically reviewed by Angelica Balingit, M.D.
Written by Kelly Crumrin
Updated on April 4, 2025

Current research shows that migraine is a type of neurological disorder. This means that it is caused by problems with the way nerve cells work inside the brain. Researchers aren’t yet sure exactly which neurological processes cause migraine attacks. During a migraine attack, different parts of the brain go through changes. This can include swelling, inflammation, the release of certain proteins, and increased sensitivity to light, sound, or touch. Researchers believe that a combination of genetic, environmental, and lifestyle factors cause people to develop migraine — and this combination is different in everyone.

Risk Factors for Migraine

Many risk factors for migraine have been identified and are being studied, but none have been pinpointed as the sole cause of migraine. Family history, other health conditions, one’s age and sex, hormone levels, sleep patterns, and certain changes in the environment can all contribute to migraine attacks. It’s important to remember that science can find patterns or links between certain factors and diseases, but just because they’re connected doesn’t mean one causes the other.

Genetics and Family History

Genetic studies have found several genes in different locations that may be connected to migraine. Some types of migraine run in families and can be passed down from parents to children.

If you have a relative who has migraine attacks, you may be more likely to have them than someone without a family history of the condition. Research shows that inherited factors may account for as much as 30 percent to 60 percent of the risk for migraine. For this reason, most researchers agree that both genetic and environmental factors contribute to the development of migraine.

Age and Sex

Age is a risk factor in migraine. Migraine attacks begin before age 40 in more than 90 percent of people with migraine.

Women are three times more likely to develop migraine than men. Women are also more likely to develop chronic migraine — defined as experiencing migraine symptoms at least 15 days in each month. About 85 percent of those with chronic migraine are women, according to the Migraine Research Foundation.

If you have migraine and menstruate, you might have spikes in symptoms at certain points in your menstrual cycle when hormones change. In fact, more than half of people with migraine notice this pattern. Menstrual migraine attacks may begin during adolescence, peak in the 30s, and taper off after menopause.

Other Health Conditions

People with migraine are more likely to have certain comorbid conditions (having two or more health conditions at the same time) than those who do not have migraine attacks. Sleep disorders, bipolar disorder, depression, anxiety, and epilepsy have all been associated with migraine.

Environmental Triggers

Researchers have identified several factors that are known for triggering migraine attacks. No one person will have all of these triggers, or even most of them. Getting to know common migraine triggers can help you notice if they happen before you have a migraine attack.


Common migraine triggers include:

  • Low blood sugar, fasting, and skipping meals
  • Mental stress
  • Physical overexertion
  • Depression or anxiety
  • Too little or too much sleep
  • Alcohol and feeling hungover
  • Caffeine
  • Tobacco
  • Hormonal changes and menstruation
  • Bright or flashing lights
  • Loud sounds
  • Sudden changes in weather
  • Dehydration
  • Certain foods

If you notice some of these factors influencing your migraine attacks, make a note of when they happen and talk it over with your doctor. Your doctor or a neurologist can help you create a treatment plan that allows you to reduce exposure to your triggers and take the best care of yourself.

​​Talk With Others Who Understand

MyMigraineTeam is the social network for people with migraine and their loved ones. On MyMigraineTeam, more than 84,000 members come together to ask questions, give advice, and share their stories with others who understand life with migraine.

What triggers your migraine attacks? Do you have a family history of migraine? Share your experience in the comments below, or start a conversation by posting on your Activities page.

A MyMigraineTeam Member

A successful brain surgery gave me side effects of chronic migraines. My pain management specialist wants to correct this issue.

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I Had Alot 6 Concussions In My Youth. Age 11 Unconscious From Car Accident. Woke Up 24hrs After. My MRI'S Clear. In 95 A Brain Cyst.No Chang

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