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What Migraine Meds Have Worked For You?

A MyMigraineTeam Member asked a question 💭
Mountain View, MO

Hello, I’m trying to research different migraine meds and if they might work for me. I have 15+ migraines a month and am very tired of the pain. I’ve had maxalt, elavil, depakote, imitrex, topamax, Botox shots and probably others that I’ve forgotten since 2003. I’m trying to get information and reviews on newer meds for migraines to have a talk with my neurologist on the 4th of next month. The meds I’m currently on (elavil, depakote, maxalt and topamax) have stopped working and I need something… read more

September 23
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A MyMigraineTeam Member

It sounds like you're dealing with a lot of pain and frustration. Here’s some information on the newer migraine medications you mentioned:

Emgality (Galcanezumab-gnlm)
- Overview: Approved by the FDA to prevent migraines in adults
- How it Works: It's a biologic drug that interferes with CGRP, a substance that dilates Show Full Answer

It sounds like you're dealing with a lot of pain and frustration. Here’s some information on the newer migraine medications you mentioned:

Emgality (Galcanezumab-gnlm)
- Overview: Approved by the FDA to prevent migraines in adults.
- How it Works: It's a biologic drug that interferes with CGRP, a substance that dilates blood vessels and contributes to pain signals and inflammation.
- Administration: Given as a subcutaneous injection once a month after initial loading doses.
- Experiences: Some users have reported a significant reduction in migraine frequency.

Ubrelvy (Ubrogepant)
- Overview: Approved by the FDA for the acute treatment of migraines in adults.
- How it Works: It's a CGRP receptor antagonist that blocks the receptor CGRP uses to react with the body.
- Administration: Taken as tablets by mouth as needed, with or without food.
- Side Effects: Common side effects include sleepiness and nausea. Allergic reactions are also possible.

Nurtec (Rimegepant)
- Note: While Nurtec is not specifically mentioned in my knowledge base, it is another CGRP receptor antagonist similar to Ubrelvy.

Additional Information
- Anti-CGRP Medications: Other options include Aimovig, Ajovy, and Emgality. Users have reported mixed experiences, with some finding significant relief and others experiencing side effects or no change in migraine frequency.

Questions to Ask Your Doctor
- Effectiveness: How effective are these medications for chronic migraine?
- Side Effects: What are the potential side effects?
- Insurance: Are these medications covered by my insurance?

Personal Experiences
- Aimovig: Some users have reported a 50% reduction in migraines and even going 30 days without a migraine.
- Emgality: Users have noted a decrease in migraine frequency.

It’s great that you’re planning to discuss these options with your neurologist. Make sure to share your treatment history and any concerns you have about side effects or effectiveness. Good luck with your appointment on the 4th of next month!

September 23

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