Aimovig (Erenumab-aooe)

Overview

Aimovig is approved by the Food and Drug Administration (FDA) to prevent migraine in adults. Aimovig is also referred to by its drug name, Erenumab-aooe. Aimovig is a biologic drug – a genetically engineered…

Ajovy (Fremanezumab-vfrm)

Overview
Ajovy is approved by the U.S. Food and Drug Administration (FDA) for the preventive treatment of migraine in adults, including both chronic and episodic forms. It is also FDA-approved for the preventive treatment…

Amerge (Naratriptan) for Migraine

The Amerge brand name brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk… read more

Atzumi (Dihydroergotamine)

Overview
Atzumi is approved by the U.S. Food and Drug Administration (FDA) for the acute treatment of migraine attacks with or without aura in adults. It is not intended for the prevention of migraine attacks or for…

Axert (Almotriptan)

The Axert brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your… read more

Botox (OnabotulinumtoxinA)

Overview
Botox is a prescription drug approved by the Food and Drug Administration (FDA) to prevent chronic migraine in adults. Botox may be prescribed in cases where headaches that last at least four hours a day occur… read more

Cafergot (Ergotamine/Caffeine)

Overview
Cafergot is a prescription drug approved by the Food and Drug Administration (FDA) to treat and prevent migraines. Cafergot is a combination drug composed of Ergotamine and Caffeine.

Ergotamine is an ergot… read more

Calan (Verapamil) for Migraine

The Calan brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your… read more

Cefaly

Overview
Cefaly is a U.S. Food and Drug Administration (FDA)-cleared medical device for the treatment and prevention of migraine in individuals aged 18 and older. Two versions of the device are available: Cefaly Enhanced…

Clinical trials

Overview
Depending on several factors, you may be eligible to participate in clinical trials studying new treatment or prevention protocols for migraines. Eligibility may be based on specifics of your condition, such as… read more

Compro (Prochlorperazine)

Overview
Compro is a prescription drug approved by the Food and Drug Administration (FDA) to treat severe nausea and vomiting in adults. Compro is also known by its drug name, Prochlorperazine.

Compro is an… read more

Covera-HS (Verapamil) for Migraine

The Covera-HS brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your… read more

Depacon (Valproate sodium)

The Depacon brand name has been discontinued in the U.S. Generic alternatives may be available.

Overview

Depacon is approved by the Food and Drug Administration (FDA) to treat several types of seizures. Depacon may also be…

Depakote (Divalproex Sodium) for Migraine

Overview
Depakote is approved by the U.S. Food and Drug Administration (FDA) for the prophylaxis (prevention) of migraine attacks in adults. Depakote is also known by its drug name, divalproex sodium.

Depakote is an…

Dexamethasone

Overview
Dexamethasone is a prescription drug approved by the Food and Drug Administration (FDA) to treat inflammation. Dexamethasone is sometimes prescribed to treat migraines. Since the FDA has not approved… read more

Elavil (Amitriptyline) for Migraine

The Elavil brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your… read more

Emgality (Galcanezumab-gnlm)

Overview

Emgality is approved by the Food and Drug Administration (FDA) to prevent migraine in adults. Emgality is also referred to by its drug name, Galcanezumab-gnlm. Emgality is a biologic drug – a genetically…

Eprontia (Topiramate) for Migraine

Overview

Eprontia is approved by the U.S. Food and Drug Administration (FDA) for the preventive treatment of migraine in people 12 years of age and older. It is used to help reduce the frequency of migraine headaches in…

Frova (Frovatriptan)

Overview
Frova is a prescription drug approved by the Food and Drug Administration (FDA) to treat acute migraine headaches with or without aura in adults. Frova is also known by its drug name, Frovatriptan.

Frova is… read more

GammaCore

Overview
A prescription device, gammaCore is approved by the U.S. Food and Drug Administration (FDA) for the acute treatment of pain associated with migraine headaches in people aged 12 years and older. It is also…

Imitrex (Sumatriptan)

Overview
Imitrex is a prescription drug approved by the Food and Drug Administration (FDA) to treat acute cluster headaches and migraine headaches with or without aura in adults. Imitrex is also known by its drug name,… read more

Inderal (Propranolol) for Migraine

The Inderal brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your… read more

Inderal LA (Propranolol Hydrochloride) for Migraine

Overview

Inderal LA is approved by the U.S. Food and Drug Administration (FDA) for the prophylaxis (prevention) of common migraine headaches. It is used to reduce the frequency and severity of migraine attacks in adults…

InnoPran XL (Propranolol)

Overview
InnoPran XL is a prescription drug approved by the Food and Drug Administration (FDA) to treat hypertension. InnoPran XL may be prescribed off-label to prevent migraines. InnoPran XL is also known by its drug… read more

Ketamine

Overview
Ketamine is a prescription drug approved by the Food and Drug Administration (FDA) to be used an an anesthetic. Ketamine is sometimes used to treat or prevent chronic migraines. Since the FDA has not approved… read more

Lopressor (Metoprolol)

Overview
Lopressor is a prescription drug approved by the Food and Drug Administration (FDA) to treat hypertension, angina, and heart attack. Lopressor may be prescribed off-label to prevent migraines. Lopressor is also… read more

Maxalt (Rizatriptan)

Overview
Maxalt is a prescription drug approved by the Food and Drug Administration (FDA) to treat acute migraine headaches with or without aura in people age 6 and older. Maxalt is also known by its drug name,… read more

Methergine (Methylergonovine)

Overview
Methergine is a prescription drug approved by the Food and Drug Administration (FDA) to control uterine hemorrhage during and after childbirth. Methergine may be prescribed off-label to treat or prevent… read more

Migergot (Caffeine/Ergotamine)

Overview
Migergot is a prescription drug approved by the Food and Drug Administration (FDA) to treat and prevent migraines. Migergot is a combination drug composed of Ergotamine and Caffeine.

Ergotamine is an ergot… read more

Migranal (Dihydroergotamine)

Overview
Migranal is a prescription drug approved by the Food and Drug Administration (FDA) to treat acute migraines. Migranal is also referred to by its drug name, Dihydroergotamine.

Migranal is an ergot alkaloid.… read more

Neurontin (Gabapentin)

Overview
Neurontin is a prescription drug approved by the Food and Drug Administration (FDA) to treat postherpetic neuralgia and some types of seizures. Neurontin may be prescribed off-label to treat migraines.… read more

Nurtec ODT (Rimegepant)

Overview

Nurtec ODT is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with acute migraine, with or without aura. Nurtec is also used as a preventative treatment of episodic…

Onzetra Xsail (Sumatriptan)

Overview
Onzetra Xsail is approved by the U.S. Food and Drug Administration (FDA) for the acute treatment of migraine with or without aura in adults. It should only be used if a clear diagnosis of migraine headache has…

Pamelor (Nortriptyline)

Overview
Pamelor is a prescription medication approved by the Food and Drug Administration (FDA) for the treatment of depression. Pamelor is also known by its drug name, Nortriptyline. Some antidepressants are… read more

Prednisone

Overview
Prednisone is a prescription drug approved by the Food and Drug Administration (FDA) to treat inflammation. Prednisone is sometimes prescribed to treat migraines. Since the FDA has not approved Prednisone… read more

Qudexy XR (Topiramate) for Migraine

Overview
Qudexy XR is approved by the U.S. Food and Drug Administration (FDA) for the preventive treatment of migraine in people 12 years of age and older. It should be prescribed for people who experience frequent…

Qulipta (Atogepant)

Overview

Qulipta is a prescription drug approved by the U.S. Food and Drug Administration (FDA) for the preventive treatment of migraine in adults. Qulipta is also referred to by its drug name, atogepant. Qulipta is a…

Reglan (Metoclopramide)

Overview
Reglan is a prescription drug approved by the Food and Drug Administration (FDA) to treat adults with gastroesophageal reflux and diabetic gastroparesis. Reglan may be prescribed off-label to treat nausea in… read more

Relpax (Eletriptan)

Overview
Relpax is a prescription drug approved by the Food and Drug Administration (FDA) to treat acute migraine headaches with or without aura in adults. Relpax is also known by its drug name, Eletriptan.

Relpax… read more

Reyvow (Lasmiditan)

The Reyvow brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your… read more

Savi Dual

Overview
The Savi Dual Migraine Therapy device is cleared by the U.S. Food and Drug Administration (FDA) for the acute and preventive treatment of migraine in people aged 12 and older. It is available only through a…

Sinequan (Doxepin)

Overview
Sinequan is a prescription drug approved by the Food and Drug Administration (FDA) to treat several types of depression. Sinequan is also referred to by its drug name, Doxepin. Some antidepressants are… read more

Sphenopalatine ganglion block

Overview
The sphenopalatine ganglion (SPG) is a cluster of nerve cells located behind the nose. The SPG is linked to the trigeminal nerve, which is involved in most headaches. Sphenopalatine ganglion block is an… read more

Symbravo (Meloxicam and Rizatriptan)

Overview

Symbravo is approved by the U.S. Food and Drug Administration (FDA) for the acute treatment of migraine with or without aura in adults. It should only be used when a clear diagnosis of migraine has been made…

Thorazine (Chlorpromazine)

Overview
Thorazine is a prescription drug approved by the Food and Drug Administration (FDA) to treat nausea and vomiting. Thorazine is also known by its drug name, Chlorpromazine.

Thorazine is an antiemitic.… read more

Topamax (Topiramate)

Overview
Topamax is a prescription drug approved by the Food and Drug Administration (FDA) to prevent migraines in people 12 and older. Topamax is also known by its drug name, Topiramate.

Topamax is an… read more

Tosymra (Sumatriptan nasal spray)

Overview
Tosymra is a prescription drug approved by the Food and Drug Administration (FDA) to treat acute migraine headaches with or without aura in adults. Tosymra is also known by its drug name, Sumatriptan.… read more

Transcutaneous electrical nerve stimulation (TENS)

Overview
A transcutaneous electrical nerve stimulation (TENS) device is a small, portable machine that generates adjustable levels of electricity to block nerve signals in those experiencing pain. For some people, TENS… read more

Treximet (Sumatriptan/Naproxen)

Overview
Treximet is a prescription drug approved by the Food and Drug Administration (FDA) to treat acute migraine headaches with or without aura in people 12 and older. Treximet is a combination drug composed of… read more

Trokendi XR (Topiramate)

Overview
Trokendi XR is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to prevent migraines in people 12 years or older. Trokendi XR is also known by its drug name, topiramate.… read more

Trudhesa (Dihydroergotamine)

Overview
Trudhesa is approved by the U.S. Food and Drug Administration (FDA) for the acute treatment of migraine with or without aura in adults. It is not approved for the preventive treatment of migraine or for treating…

Ubrelvy (Ubrogepant)

Overview

Ubrelvy is a prescription drug approved by the U.S. Food and Drug Administration (FDA) as an acute treatment for migraine in adults. Ubrelvy is also referred to by its drug name, ubrogepant. Ubrelvy is a…

Verelan (Verapamil)

Overview
Verelan is a prescription drug approved by the Food and Drug Administration (FDA) to treat hypertension. Verelan may be prescribed off-label to prevent migraines. Verelan is also known by its drug name,… read more

Vivactil (Protriptyline)

Overview
Vivactil is a prescription drug approved by the Food and Drug Administration (FDA) to treat depression in people who are under close medical supervision. Vivactil is also known by its drug name, Protriptyline.… read more

Vyepti (Eptinezumab-jjmr)

Overview

Vyepti is a prescription drug approved by the U.S. Food and Drug Administration (FDA) as preventative treatment for migraine in adults. Vyepti is also referred to by its drug name, eptinezumab-jjmr. Vyepti is a…

Zavzpret (Zavegepant)

Overview
Zavzpret is approved by the U.S. Food and Drug Administration (FDA) for the acute treatment of migraine with or without aura in adults. It is not indicated for the preventive treatment of migraine. Zavzpret is…

Zembrace SymTouch (sumatriptan succinate)

Overview
Zembrace SymTouch is a prescription drug approved by the U.S. Food and Drug Administration (FDA) as an acute (short-term) treatment for migraine in adults. Zembrace SymTouch is also referred to by its drug… read more

Zestril (Lisinopril)

Overview
Zestril is a prescription drug approved by the Food and Drug Administration (FDA) to treat hypertension and heart failure. Zestril may be prescribed off-label to prevent migraines. Zestril is also known by its… read more

Zoloft (Sertraline)

Overview
Zoloft is a prescription drug approved by the Food and Drug Administration (FDA) to treat major depressive disorder in adults. Zoloft is also known by its drug name, Sertraline. Some antidepressants are… read more

Zomig (Zolmitriptan)

Overview

Zomig is a prescription drug approved by the Food and Drug Administration (FDA) to treat acute migraine headaches with or without aura in people 12 years and older. Zomig is also known by its drug name…